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Native Transferrin Receptor (TFR)
Native Transferrin Receptor (TFR)
- 中文名称：
- Native Transferrin Receptor (TFR)
- 英文名称：
- Native Transferrin Receptor (TFR)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA135544
- 规格：
- 0.01 mg|0.05 mg|0.1 mg|0.2 mg|0.5 mg
- 保存建议：
- Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
- 货期：
- 6-8周
- 纯度：
- > 95%
- 产品形式：
- Supplied as lyophilized form in 50mM TRIS, 200mM NaCl
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Transferrin receptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. It imports iron by internalizing the transferrin-iron complex through receptor-mediated endocytosis. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. This protein binds to the hairpin like structure (IRE) that is in the 3' UTR of the TfR receptor. Once binding occurs, degradation of mRNA of IRE is inhibited.
