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Human COVID-19 Nucleocapsid (NP) IgM Antibody ELISA Kit
Human COVID-19 Nucleocapsid (NP) IgM Antibody ELISA Kit
- 中文名称:
- Human COVID-19 Nucleocapsid (NP) IgM Antibody ELISA Kit
- 英文名称:
- Human COVID-19 Nucleocapsid (NP) IgM Antibody ELISA Kit
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA23768
- 规格:
- 48-Strip-Wells|96-Strip-Wells|2x96-Strip-Wells|3x96-Strip-Wells|4x96-Strip-Wells
- 保存建议:
- 将所有试剂储存在2-8摄氏度
- 货期:
- 6-8周
- 检测种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways.
Principle of the Assay: The human COVID-19 IgM antibody ELISA is made from the human IgM antibody coated microtiter plate, 2019-nCoV N protein-HRP and other reagents. It applies the capture ELISA principle to test the IgM against 2019-nCoV in human serum. In the test, the coated human IgM antibody combine with COVID-19 IgM antibody in serum, then add 2019-nCoV N protein -HRP to specifically bind with complex of antibody-IgM on the microplate. With the TMB substrate, it will generate an amount of color. The depth of color is relative with the content of the COVID-19 IgM antibody, when the value of color is greater than the cut-off value, the human has been infected with the 2019-nCoV.
Intended Uses: This Human COVID-19 Nucleocapsid (N) IgM ELISA kit is a 2-hour ELISA for the detection of the COVID-19 IgM antibody of human serum. This ELISA kit for research use only, not for therapeutic or diagnostic applications!