
-
Human Polymeric Immunoglobulin Receptor, PIGR Primacu ELISA Kit
Human Polymeric Immunoglobulin Receptor, PIGR Primacu ELISA Kit
- 中文名称:
- Human Polymeric Immunoglobulin Receptor, PIGR Primacu ELISA Kit
- 英文名称:
- Human Polymeric Immunoglobulin Receptor, PIGR Primacu ELISA Kit
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA124098
- 规格:
- 96-Strip-Wells|2x96-Strip-Wells|5x96-Strip-Wells
- 保存建议:
- Store at 2-8 degree C
- 货期:
- 6-8周
- 检测种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.