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Human Plexin Domain-Containing Protein 1, PLXDC1 Primacu ELISA Kit
Human Plexin Domain-Containing Protein 1, PLXDC1 Primacu ELISA Kit
- 中文名称：
- Human Plexin Domain-Containing Protein 1, PLXDC1 Primacu ELISA Kit
- 英文名称：
- Human Plexin Domain-Containing Protein 1, PLXDC1 Primacu ELISA Kit
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA124107
- 规格：
- 96-Strip-Wells|2x96-Strip-Wells|5x96-Strip-Wells
- 保存建议：
- Store at 2-8 degree C
- 货期：
- 6-8周
- 检测种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin family. PLXDC1/TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1/TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1/TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1/TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1/TEM3 may be a molecular target for new test and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1/TEM3 interacts with NID1. It may also interact with CTTN.
