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Human Platelet-Derived Growth Factor Receptor Beta, PDGFRB Primacu ELISA Kit
Human Platelet-Derived Growth Factor Receptor Beta, PDGFRB Primacu ELISA Kit
- 中文名称:
- Human Platelet-Derived Growth Factor Receptor Beta, PDGFRB Primacu ELISA Kit
- 英文名称:
- Human Platelet-Derived Growth Factor Receptor Beta, PDGFRB Primacu ELISA Kit
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA124165
- 规格:
- 96-Strip-Wells|2x96-Strip-Wells|5x96-Strip-Wells
- 保存建议:
- Store at 2-8 degree C
- 货期:
- 6-8周
- 检测种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-beta was correlated with depth of cancer invasion at statistically significant level. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy