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Mouse Thrombospondin Type-1 Domain-Containing Protein 1, Thsd1 Primacu ELISA Kit
Mouse Thrombospondin Type-1 Domain-Containing Protein 1, Thsd1 Primacu ELISA Kit
- 中文名称:
- Mouse Thrombospondin Type-1 Domain-Containing Protein 1, Thsd1 Primacu ELISA Kit
- 英文名称:
- Mouse Thrombospondin Type-1 Domain-Containing Protein 1, Thsd1 Primacu ELISA Kit
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA124181
- 规格:
- 96-Strip-Wells|2x96-Strip-Wells|5x96-Strip-Wells
- 保存建议:
- Store at 2-8 degree C
- 货期:
- 6-8周
- 检测种属:
- Mouse
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.