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Human Hepatocyte Growth Factor Receptor, MET Primacu ELISA Kit
Human Hepatocyte Growth Factor Receptor, MET Primacu ELISA Kit
- 中文名称:
- Human Hepatocyte Growth Factor Receptor, MET Primacu ELISA Kit
- 英文名称:
- Human Hepatocyte Growth Factor Receptor, MET Primacu ELISA Kit
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA124187
- 规格:
- 96-Strip-Wells|2x96-Strip-Wells|5x96-Strip-Wells
- 保存建议:
- Store at 2-8 degree C
- 货期:
- 6-8周
- 检测种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy