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Infliximab (Remicade) PK
Infliximab (Remicade) PK
- 中文名称：
- Infliximab (Remicade) PK
- 英文名称：
- Infliximab (Remicade) PK
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA13586
- 规格：
- 96 Wells|2x96 Wells|3x96 Wells|4x96 Wells|5x96 Wells
- 保存建议：
- Store kit components at -20 degree C unless specified otherwise. Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
- 货期：
- 6-8周
- 检测种属：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Background: Infliximab (Remicade) is a chimeric monoclonal antibody against tumour necrosis factor alpha (TNF- alpha). Infliximab neutralizes the biological activity of TNF- alpha by binding with high affinity to the soluble (free floating in the blood) and transmembrane forms of TNF-alpha, and thereby blocks binding of TNF-alpha with its receptors. The Infliximab ELISA kit is designed to measure free Infliximab with high specificity and sensitivity in biological matrices.
Principle of the Assay: This assay employs the sandwich enzyme immunoassay technique. Anti- Infliximab is coated onto a 96 well microplate. Calibrator, quality control samples (if desired) and test samples are pipetted into the appropriate wells. Infliximab present in biological matrices is bound by the immobilized anti- Infliximab antibody. After washing away any unbound substances, enzyme linked anti- Infliximab antibody is added to the wells. This antibody is developed and purified specifically against truncated Remicade (domain residing in Fc portion of the Remicade molecule). The plate is washed to remove any unbound antibody-enzyme reagent and a substrate solution is added to the wells for color development. The color development is proportional to the amount of Infliximab present in test samples. The color development is stopped and the intensity of the color is measured.
