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Omalizumab (Xolair) PK ELISA Kit
Omalizumab (Xolair) PK ELISA Kit
- 中文名称：
- Omalizumab (Xolair) PK ELISA Kit
- 英文名称：
- Omalizumab (Xolair) PK ELISA Kit
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA13592
- 规格：
- 96 Wells|2x96 Wells|3x96 Wells|4x96 Wells|5x96 Wells
- 保存建议：
- Store kit components at -20 degree C unless specified otherwise. Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
- 货期：
- 6-8周
- 检测种属：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Principle of the Assay: This assay employs the sandwich enzyme immunoassay technique. Anti-Cetuximab is coated onto a 96 well microplate. Calibrator, quality control samples (if desired) and test samples are pipetted into the appropriate wells. Cetuximab present in biological matrices is bound by the immobilized anti-Cetuximab antibody. After washing away any unbound substances, enzyme linked anti-Cetuximab antibody is added to the wells. This antibody is developed and purified specifically against truncated Erbitux (domain residing in Fc portion of the Erbitux molecule). The plate is washed to remove any unbound antibody-enzyme reagent and a substrate solution is added to the wells for color development. The color development is proportional to the amount of Cetuximab present in test samples. The color development is stopped and the intensity of the color is measured!!Background/Introduction: Cetuximab (Erbitux) is a chimeric IgG1 monoclonal antibody that binds the extra-cellular domain of the epidermal growth factor receptor (EGFR). Cetuximab inhibits activation of the EGFR and the associated downstream signaling. Furthermore Cetuximab induces antibody-mediated receptor dimerization, internalization and degradation leading to receptor down-regulation, and antibody-dependent cellular cytotoxicity that could contribute to its antitumor effect. The Cetuximab ELISA kit is designed to measure Cetuximab with high specificity and enhanced sensitivity in serum or plasma.
