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Pembrolizumab(Keytruda) Pharmacokinetic
Pembrolizumab(Keytruda) Pharmacokinetic
- 中文名称：
- Pembrolizumab(Keytruda) Pharmacokinetic
- 英文名称：
- Pembrolizumab(Keytruda) Pharmacokinetic
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA13593
- 规格：
- 96 Wells|2x96 Wells|3x96 Wells|4x96 Wells|5x96 Wells
- 保存建议：
- Store kit components at -20 degree C unless specified otherwise. Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
- 货期：
- 6-8周
- 检测种属：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Background: Pembrolizumab (Trade name Keytruda) is a human monoclonal antibody used to block the action of Programmed Cell Death Protein 1(PD-1). Upregulation of PD-1 ligands on tumor cells can allow the tumor to evade anti-tumor immune response. By blocking PDL1 and PD-L2 binding to PD-1, Pembrolizumab induces an anti-tumor immune response by allowing full activation of the anti-tumor T cell response. Thus, Pembrolizumab acts as a checkpoint inhibitor to stimulate immune responses to eliminate cancer cells. The Pembrolizumab ELISA kit is designed to measure free Pembrolizumab with high specificity and sensitivity. The assay design uses a pair of antibodies allowing detection of whole Pembrolizumab molecules in biological matrices.
Principle of the Assay: This assay employs the sandwich enzyme immunoassay technique. Standards and test samples are pipetted into the appropriate wells. Pembrolizumab present in biological matrices is bound by the immobilized capture antibody. After washing away any unbound substances, enzyme linked detection antibody is added to the wells. The plate is washed to remove any unbound antibodyenzyme reagent and a substrate solution is added to the wells for color development. The color development is proportional to the amount of Pembrolizumab present in test samples.
