-
Myeloperoxidase (MPO) Peroxidation Activity Fluorometric Assay Kit
Myeloperoxidase (MPO) Peroxidation Activity Fluorometric Assay Kit
- 中文名称：
- Myeloperoxidase (MPO) Peroxidation Activity Fluorometric Assay Kit
- 英文名称：
- Myeloperoxidase (MPO) Peroxidation Activity Fluorometric Assay Kit
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA177769
- 规格：
- 96 Tests|500 Assays|2x500 Assays|3x500 Assays|4x500 Assays
- 保存建议：
- Store at -20 degree C. Valid for 12 months
- 货期：
- 6-8周
- 检测种属：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Intended Uses: This kit can be used to detect Myeloperoxidase (MPO) Peroxidation activity in serum, plasma and tissue samples.
Principle of the Assay: Under the catalysis of peroxidase, hydrogen peroxide can oxidize the nonfluorescent probe into the fluorescent substance, and its fluorescence intensity is proportional to the total peroxidase activity in the sample. This kit specifically inhibits the peroxidase activity of MPO in the sample through an MPO enzyme inhibitor, thus distinguishing the peroxidase activity of MPO in the sample from that of other peroxidases.
Background/Introduction: Myeloperoxidase is a heme-containing cationic glycoprotein that belongs to the heme peroxidase family in mammals. MPO is a dimer formed by polymerization of two subunits. Each subunit contains a heavy chain and a light chain. MPO is abundant in the azuropathic granules of polymorphonuclear leukocytes (PMNLs) and a small number in monocytes and macrophages. Studies have shown that MPO plays an important role in the generation of oxidants and host defense in neutrophils and is closely related to the pathogenesis of many diseases, including cardiovascular disease, lung injury and cancer.
