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Recombinant Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A), partial
Recombinant Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A), partial
- 中文名称：
- Recombinant Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A), partial
- 英文名称：
- Recombinant Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A), partial
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA116174
- 规格：
- 0.02 mg (E-Coli)|0.1 mg (E-Coli)|1 mg (E-Coli)|5x1 mg (E-Coli)|
- 保存建议：
- Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
- 货期：
- 6-8周
- 纯度：
- Greater or equal to 85% purity as determined by SDS-PAGE.
- 产品形式：
- Lyophilized or liquid (Format to be determined during the manufacturing process)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
