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3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Inhibitor Screening Kit
3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Inhibitor Screening Kit
- 中文名称：
- 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Inhibitor Screening Kit
- 英文名称：
- 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Inhibitor Screening Kit
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA179718
- 规格：
- 48 Tests|96 Tests|2x96 Tests|3x96 Tests|4x96 Tests
- 保存建议：
- This product can be stored at -20 degree C for 12 months with shading light.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) is the rate-limiting enzyme of mevalonate pathway, which is the metabolic pathway of acetyl-CoA to produce cholesterol.This detection kit can screen inhibitors of HMGR, which is an important tool for basic research of cholesterol and other related metabolic pathways.
The detection principle of this kit: HMGR catalyzed substrate reaction consumes NADPH, and the absorbance decreases at 340nm. The addition of inhibitors will inhibit HMGR enzyme activity, resulting in a decrease in the rate of absorbance decline. The inhibition rate can be calculated by measuring the change value of absorbance.
