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Etomoxir
Etomoxir
- 中文名称：
- Etomoxir
- 英文名称：
- Etomoxir
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA201898
- 规格：
- 5 mg|10 mg|25 mg|50 mg|100 mg
- 保存建议：
- Store at -20 degree C for >2 years.
- 货期：
- 6-8周
- 纯度：
- >98% (HPLC)
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
An irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) that inhibits fatty acid beta-oxidation in rat liver with IC50 of 5-20nM; affects ketogenesis, cholesterol synthesis, and gluconeogenesis both in vitro and in vivo; decreases viability in LNCaP, VCaP, and patient-derived benign and prostate cancer cells, associated with decreased AR expression, decreased mTOR signaling, and increased caspase-3 activation; decreases xenograft growth in mice. Heart Failure Phase 2 Discontinued
