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Tesirine
Tesirine
- 中文名称:
- Tesirine
- 英文名称:
- Tesirine
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA201910
- 规格:
- 1 mg|2x1 mg|3x1 mg|4x1 mg|
- 保存建议:
- Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
- 货期:
- 6-8周
- 纯度:
- Analytical data HPLC: 98% purity
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Tesirine (SG3249) is a cathepsin B-cleavable valine-alanine pyrrolobenzodiazepine (PBD) dimer as antibody-drug conjugate (ADC) payload; Tesirine (SG3249) was designed to combine potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics; Rovalpituzumab tesirine is a first-in-class antibody-drug conjugate directed against delta-like protein 3 (DLL3), a novel target identified in tumour-initiating cells and expressed in small-cell lung cancer.