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Tpl2 Kinase Inhibitor (hydrochloride)
Tpl2 Kinase Inhibitor (hydrochloride)
- 中文名称：
- Tpl2 Kinase Inhibitor (hydrochloride)
- 英文名称：
- Tpl2 Kinase Inhibitor (hydrochloride)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA227037
- 规格：
- INQUIRE
- 保存建议：
- 粉末:-20摄氏度存放3年< br >在溶剂中:-80摄氏度存放2年
- 货期：
- 6-8周
- 纯度：
- 98%
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 uM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = 40, 180, 400, 110, and 400 uM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-alpha production in isolated human monocytes and whole blood (IC50s = 0.7 and 8.5 uM, respectively). It enhances differentiation induced by calcitriol in HL-60 and U937 leukemia cells when used at a concentration of 5 uM.2Tpl2 kinase inhibitor (5 uM) inhibits the proliferation of KG-1a leukemia cells.3
