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Deltorphin II (trifluoroacetate salt)
Deltorphin II (trifluoroacetate salt)
- 中文名称:
- Deltorphin II (trifluoroacetate salt)
- 英文名称:
- Deltorphin II (trifluoroacetate salt)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA227199
- 规格:
- INQUIRE
- 保存建议:
- 粉末:-20摄氏度存放3年< br >在溶剂中:-80摄氏度存放2年
- 货期:
- 6-8周
- 纯度:
- 98%
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Deltorphin II is a peptide agonist of delta2-opioid receptors.1,2It is selective for delta-opioid receptors over u- and kappa-opioid receptors in radioligand bindings assays (Kis = 0.0033, 1, and 1 uM, respectively) and induces [35S]GTPgammaS binding in mouse brain membrane preparations (EC50= 0.034 uM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the delta2-opioid receptor antagonist naltriben but not the delta1-opioid receptor antagonist BNTX.3Intrathecal administration of deltorphin II (15 ug/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.4