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Defensin HNP-3 (human)(trifluoroacetate salt)
Defensin HNP-3 (human)(trifluoroacetate salt)
- 中文名称:
- Defensin HNP-3 (human)(trifluoroacetate salt)
- 英文名称:
- Defensin HNP-3 (human)(trifluoroacetate salt)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA227375
- 规格:
- INQUIRE
- 保存建议:
- 粉末:-20摄氏度存放3年< br >在溶剂中:-80摄氏度存放2年
- 货期:
- 6-8周
- 纯度:
- 98%
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 ug/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 uM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV).