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Okadaic acid ammonium salt
Okadaic acid ammonium salt
- 中文名称:
- Okadaic acid ammonium salt
- 英文名称:
- Okadaic acid ammonium salt
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA227885
- 规格:
- INQUIRE
- 保存建议:
- 粉末:-20摄氏度存放3年< br >在溶剂中:-80摄氏度存放2年
- 货期:
- 6-8周
- 纯度:
- 98%
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC 50 =0.1-0.3 nM), and inhibits PP1 (IC 50 =15-50 nM), PP3 (IC 50 =3.7-4 nM), PP4 (IC 50 =0.1 nM), PP5 (IC 50 =3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation.