![Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]](/skin/notimg.webp)
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Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]
Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]
- 中文名称：
- Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]
- 英文名称：
- Rabbit anti-PBRM1 Recombinant Monoclonal Antibody [BL-39-2C3]
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA23796
- 规格：
- 0.02 mL|0.1 mL|2x0.1 mL|5x0.02 mL|3x0.1 mL
- 保存建议：
- 储存在2-8摄氏度下< br >保质期:自收到之日起1年
- 货期：
- 6-8周
- 纯度：
- Purified
- 产品形式：
- Liquid. Whole IgG. Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PBRM1 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PBRM1 has been proposed to function as a tumor suppressor protein. Recently, PBRM1 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21.
