![Rabbit anti-TIM3 Recombinant Monoclonal Antibody [BLR033F]](/skin/notimg.webp)
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Rabbit anti-TIM3 Recombinant Monoclonal Antibody [BLR033F]
Rabbit anti-TIM3 Recombinant Monoclonal Antibody [BLR033F]
- 中文名称：
- Rabbit anti-TIM3 Recombinant Monoclonal Antibody [BLR033F]
- 英文名称：
- Rabbit anti-TIM3 Recombinant Monoclonal Antibody [BLR033F]
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA23803
- 规格：
- 0.01 mL|0.1 mL|5x0.01 mL|2x0.1 mL|3x0.1 mL
- 保存建议：
- 储存在2-8摄氏度下< br >保质期:自收到之日起1年
- 货期：
- 6-8周
- 纯度：
- Purified
- 产品形式：
- Liquid. Whole IgG. Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
TIM3 (HAVCR2) is a cell surface receptor implicated in modulating innate and adaptive immune responses. It is generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses, and promotes immunological tolerance. In CD8+ cells TIM3 attenuates TCR-induced signaling, specifically by blocking NF-kappaB and NFAT promoter activities resulting in the loss of IL-2 secretion. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TDQ0].
