![Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR217K]](/skin/notimg.webp)
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Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR217K]
Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR217K]
- 中文名称：
- Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR217K]
- 英文名称：
- Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR217K]
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA23870
- 规格：
- 0.01 mL|0.1 mL|5x0.01 mL|2x0.1 mL|3x0.1 mL
- 保存建议：
- 储存在2-8摄氏度下< br >保质期:自收到之日起1年
- 货期：
- 6-8周
- 纯度：
- Purified
- 产品形式：
- Liquid. Whole IgG. Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.
