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FCGR2A Antibody
FCGR2A Antibody
- 中文名称:
- FCGR2A Antibody
- 英文名称:
- FCGR2A Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA243816
- 规格:
- 0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议:
- Upon receipt, store at -20 degree or -80 degree Avoid repeated freeze.
- 货期:
- 6-8周
- 纯度:
- Affinity-chromatography
- 产品形式:
- Liquid
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Description: The recombinant FCGR2A monoclonal antibody is produced through a series of steps: first, sequencing the FCGR2A monoclonal antibody gene; second, incorporating the gene into a plasmid vector; third, introducing the recombinant vector into a host cell line; fourth, and finally, purifying the FCGR2A recombinant monoclonal antibody from the cell culture supernatant using affinity chromatography. The FCGR2A monoclonal antibody is derived from the FCGR2A antibody-producing hybridomas, using a synthesized peptide from human FCGR2A as the immunogen. The recombinant FCGR2A monoclonal antibody is highly recommended for ELISA and WB applications to detect human FCGR2A protein. The FCGR2A protein, also known as CD32a, is a member of the Fc gamma receptor family and plays a key role in the immune response. Specifically, it is an activating receptor expressed on the surface of certain immune cells, such as macrophages, monocytes, and dendritic cells, where it binds to the Fc portion of immunoglobulin G (IgG) antibodies. This binding triggers a signaling cascade that leads to various cellular responses, including phagocytosis, antibody-dependent cell-mediated cytotoxicity (ADCC), and the release of inflammatory cytokines. The FCGR2A protein is thus an important mediator of the body's defense against pathogens and foreign substances.