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Mouse LIMPII/SR-B2 HEK293 Overexpression Lysate
Mouse LIMPII/SR-B2 HEK293 Overexpression Lysate
- 中文名称：
- Mouse LIMPII/SR-B2 HEK293 Overexpression Lysate
- 英文名称：
- Mouse LIMPII/SR-B2 HEK293 Overexpression Lysate
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA257381
- 规格：
- 0.3 mg|2x0.3 mg|3x0.3 mg|4x0.3 mg|5x0.3 mg
- 保存建议：
- Store at 4 degree C for up to twelve months from date of receipt. After re-dissolution, aliquot and store at -80 degree C for up to twelve months. Avoid repeated freeze-thaw cycles.
Samples are stable for up to twelve months from date of receipt.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- 1x Sample Buffer (1x modified RIPA buffer+1x SDS loading buffer).
Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses' propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, and may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.
This Mouse LIMPII/SR-B2 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of LIMPII/SR-B2 protein from the overexpression lysate was verified.
