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OX40L/TNFSF4 Protein, Mouse, Recombinant (ECD, His Tag)
OX40L/TNFSF4 Protein, Mouse, Recombinant (ECD, His Tag)
- 中文名称:
- OX40L/TNFSF4 Protein, Mouse, Recombinant (ECD, His Tag)
- 英文名称:
- OX40L/TNFSF4 Protein, Mouse, Recombinant (ECD, His Tag)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA257492
- 规格:
- 0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议:
- Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping: They are shipped out with blue ice pack
- 货期:
- 6-8周
- 纯度:
- >95 % as determined by SDS-PAGE.
- 产品形式:
- Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig-and CD4-stimulated B cells, this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.