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B7-H3 Protein, Human, Recombinant (ECD, hFc Tag)
B7-H3 Protein, Human, Recombinant (ECD, hFc Tag)
- 中文名称：
- B7-H3 Protein, Human, Recombinant (ECD, hFc Tag)
- 英文名称：
- B7-H3 Protein, Human, Recombinant (ECD, hFc Tag)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA257968
- 规格：
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议：
- Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C upon receiving.
Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- >95% as determined by SDS-PAGE
>90% as determined by SEC- HPLC.
- 产品形式：
- Lyophilized from sterile PBS, pH7.4. 5% Trehalose, 5% Mannitol, 0.01% Tween-80
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Background: B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.
