-
LILRB3 Protein, Mouse, Recombinant (His Tag)
LILRB3 Protein, Mouse, Recombinant (His Tag)
- 中文名称：
- LILRB3 Protein, Mouse, Recombinant (His Tag)
- 英文名称：
- LILRB3 Protein, Mouse, Recombinant (His Tag)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258202
- 规格：
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议：
- Store it under sterile conditions at -20 degree C to -80 degree C upon receiving.
Samples are stable for up to twelve months from date of receipt at -70 degree C
Recommend to aliquot the protein into smaller quantities for optimal storage
Avoid repeated freeze/thaw cycles
- 货期：
- 6-8周
- 纯度：
- > 95% as determined by SDS-PAGE
> 85% as determined by SEC-HPLC
- 产品形式：
- Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Background: Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein that belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3/CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3/CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in the modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3/CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.
