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Recombinant Phospho-p70 S6 Kinase 1 (Thr389) Antibody, Rabbit Monoclonal
Recombinant Phospho-p70 S6 Kinase 1 (Thr389) Antibody, Rabbit Monoclonal
- 中文名称：
- Recombinant Phospho-p70 S6 Kinase 1 (Thr389) Antibody, Rabbit Monoclonal
- 英文名称：
- Recombinant Phospho-p70 S6 Kinase 1 (Thr389) Antibody, Rabbit Monoclonal
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA258873
- 规格：
- 0.02 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议：
- 此类产品特殊，请按照说明书指示
- 货期：
- 6-8周
- 纯度：
- Protein A
- 产品形式：
- Liquid; 0.2um filtered solution in PBS
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase (S6K). S6K can be activated by mitogenic stimuli such as growth factors, insulin and cytokines. It phosphorylates the ribosomal protein S6. PS6K also phosphorylates other proteins such as elF4B, eEF2K and SKAR. It is a crucial effector of mTOR(rapamycin) signaling. PS6K is dissociated from the EIF3 complex and activated upon mitogenic stimulation, phosphorylation by the mammalian target of mTOR complex 1 (mTORC1). Its active form then phosphorylates and activates several substrates in the preinitiation complex, including the EIF2B complex and the cap-binding complex component EIF4B. PS6K also functions in cell proliferation, cell growth and cell cycle progression.
