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Recombinant Anti-CD47 Antibody, Rabbit Monoclonal
Recombinant Anti-CD47 Antibody, Rabbit Monoclonal
- 中文名称:
- Recombinant Anti-CD47 Antibody, Rabbit Monoclonal
- 英文名称:
- Recombinant Anti-CD47 Antibody, Rabbit Monoclonal
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA259143
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- 此类产品特殊,请按照说明书指示
- 货期:
- 6-8周
- 纯度:
- Protein A
- 产品形式:
- Liquid; 0.2um filtered solution in PBS
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.