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Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified
Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified
- 中文名称:
- Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified
- 英文名称:
- Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA259304
- 规格:
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议:
- Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- 货期:
- 6-8周
- 纯度:
- >= 90% as determined by SDS-PAGE. >= 95% as determined by SEC-HPLC.
- 产品形式:
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 3 mM CaCl2, 10% Glycerol, 0.1 M Arg, pH 8.0. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Cadherin 10 (CDH10) is a type II cadherin predominantly expressed in the brain, putatively involved in axon outgrowth and guidance. Also known to mediate calcium-dependent cell-cell adhesion and maintain the correct balance between excitation and inhibition in neuronal dendrites., CDH 10 has a large N-terminal extracellular domain (containing 5 cadherin motif subdomains which appear to determine the specificity of the protein's homophilic cell adhesion activity), a single membrane-spanning domain, and a small, conserved C-terminal cytoplasmic domain. CDH10 spans 157.7kb on chromosome 5 and produces two transcript variants. Mutations and loss of expression of this protein have been observed in multiple cancer types, including gastric, colorectal, pancreatic, endometrial and lung. Genetic variations nearby the CDH10 genetic region have been associated with autism.