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Recombinant Human APLP2 Protein (ECD, His Tag), HPLC-verified
Recombinant Human APLP2 Protein (ECD, His Tag), HPLC-verified
- 中文名称：
- Recombinant Human APLP2 Protein (ECD, His Tag), HPLC-verified
- 英文名称：
- Recombinant Human APLP2 Protein (ECD, His Tag), HPLC-verified
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA259328
- 规格：
- 0.1 mg|1 mg|2x1 mg|3x1 mg|4x1 mg
- 保存建议：
- Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- 货期：
- 6-8周
- 纯度：
- >= 90% as determined by SDS-PAGE. >= 95% as determined by SEC-HPLC.
- 产品形式：
- Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
YWK-II protein/APLP2 is a member of an evolutionarily conserved APP family that includes amyloid precursor protein (APP) and amyloid precursor-like protein-1 (APLP1). YWK-II/APLP2 functions as a novel G(0)-protein-coupled receptor for Müllerian inhibiting substance (MIS) in cell survival. Human leukocyte antigen-B-associated transcript 3 (Bat3), an important regulator involved in apoptosis, can interact with YWK-II/APLP2 and enhance its stability by reducing its ubiquitylation and degradation by the ubiquitin-proteasome system. APLP2 is specifically required for proper cell cycle exit of neuronal progenitors, and has a distinct role in priming cortical progenitors for neuronal differentiation. Amyloid precursor like protein-2 (APLP2), a closely related homolog to AbetaPP, also possesses a highly conserved KPI domain. AbetaPP and APLP2 share overlapping anticoagulant functions with regard to regulating thrombosis after cerebral vascular injury.
