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Phospho-HER2/ErbB2 (Tyr1221,1222) Antibody, Rabbit MAb
Phospho-HER2/ErbB2 (Tyr1221,1222) Antibody, Rabbit MAb
- 中文名称：
- Phospho-HER2/ErbB2 (Tyr1221,1222) Antibody, Rabbit MAb
- 英文名称：
- Phospho-HER2/ErbB2 (Tyr1221,1222) Antibody, Rabbit MAb
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA259501
- 规格：
- 0.02 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议：
- This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
- 货期：
- 6-8周
- 纯度：
- Protein A
- 产品形式：
- Liquid; 10 mM sodium HEPES, 150 mM NaCl, 100ug/mL BSA, 50% glycerol, pH 7.5
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
