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Recombinant Influenza A virus Matrix protein 2 (M2)
Recombinant Influenza A virus Matrix protein 2 (M2)
- 中文名称:
- Recombinant Influenza A virus Matrix protein 2 (M2)
- 英文名称:
- Recombinant Influenza A virus Matrix protein 2 (M2)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA26944
- 规格:
- 0.02 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议:
- Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
- 货期:
- 6-8周
- 纯度:
- Greater or equal to 85% purity as determined by SDS-PAGE.
- 产品形式:
- Liquid containing glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation (By similarity).