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2019-nCoV E protein; 2019-nCoV sM protein
2019-nCoV E protein; 2019-nCoV sM protein
- 中文名称：
- 2019-nCoV E protein; 2019-nCoV sM protein
- 英文名称：
- 2019-nCoV E protein; 2019-nCoV sM protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA27952
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Ships on dry ice.
Short Term: -20°C
Long Term: -80°C
- 货期：
- 6-8周
- 纯度：
- Purity: Greater than 85% as determined by reducing SDS-PAGE.
Purification: Affinity purification chromatography.
- 产品形式：
- Supplied as a 0.2 uM filtered solution of 20mM Tris–HCl, 200mM NaCl, pH 8.0
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Recombinant 2019-nCoV Envelope Protein is produced by our E.coli expression system and the target gene encoding Met1-Val75 is expressed with a BBP, 6His tag at the N-terminus.
Background: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
