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Recombinant Human TNFRSF25/DR3/TNFRSF12 Protein
Recombinant Human TNFRSF25/DR3/TNFRSF12 Protein
- 中文名称：
- Recombinant Human TNFRSF25/DR3/TNFRSF12 Protein
- 英文名称：
- Recombinant Human TNFRSF25/DR3/TNFRSF12 Protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA281432
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|
- 保存建议：
- Store at -20°C. Store the lyophilized protein at -20°C to -80°C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week. Avoid repeated freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- >95% by SDS-PAGE.
- 产品形式：
- Lyophilized from a 0.22um filtered solution of PBS, pH 7.4
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Recombinant Human TNFRSF25/DR3/TNFRSF12 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Gln25-Phe201) of human TNFRSF25/DR3/TNFRSF12 (Accession #Q93038) fused with an Fc tag at the C-terminus.
Background: This protein is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
