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Recombinant Human IL-28A/IL28A Protein
Recombinant Human IL-28A/IL28A Protein
- 中文名称：
- Recombinant Human IL-28A/IL28A Protein
- 英文名称：
- Recombinant Human IL-28A/IL28A Protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA282162
- 规格：
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|2x0.1 mg
- 保存建议：
- Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
- 货期：
- 6-8周
- 纯度：
- >97% by SDS-PAGE.
- 产品形式：
- Lyophilized from a 0.22um filtered solution of PBS, pH7.4.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant Human IL-28A/IL28A Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val26-Val200) of human IL-28A/IL28A (Accession #NP_742150.1) fused with a 6×His tag at the C-terminus.
Background: IL 28A (Interferon-lambda 2; IFN-lambda 2), IL-28B/IFN-lambda 3, and IL-29/IFN-lambda 1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. IL 28A, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine which are expression can be induced by viral infection.In the liver, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
