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Recombinant Mouse EGFR/HER1 Protein
Recombinant Mouse EGFR/HER1 Protein
- 中文名称:
- Recombinant Mouse EGFR/HER1 Protein
- 英文名称:
- Recombinant Mouse EGFR/HER1 Protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA283396
- 规格:
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|2x0.1 mg
- 保存建议:
- Store at -20 degree C. Store the lyophilized protein at -20 degree C to -80 degree C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
- 货期:
- 6-8周
- 纯度:
- >95% by Tris-Bis PAGE and HPLC.
- 产品形式:
- Lyophilized from a 0.22 um filtered solution of PBS, pH7.4.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-alpha, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.