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HIF-1 beta Rabbit mAb
HIF-1 beta Rabbit mAb
- 中文名称:
- HIF-1 beta Rabbit mAb
- 英文名称:
- HIF-1 beta Rabbit mAb
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA315229
- 规格:
- 0.05 mL|0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL
- 保存建议:
- Store at +4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.
- 货期:
- 6-8周
- 纯度:
- Affinity-chromatography
- 产品形式:
- Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
HIF-1beta is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1beta plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1beta expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1beta plays an important role in pancreatic beta-cell function.