-
Fluor 488-Phalloidin
Fluor 488-Phalloidin
- 中文名称：
- Fluor 488-Phalloidin
- 英文名称：
- Fluor 488-Phalloidin
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA332505
- 规格：
- 500 Tests|2x500 Tests|3x500 Tests|4x500 Tests|5x500 Tests
- 保存建议：
- Store at -20°C for 12 months, protect from light.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Principle of the Assay: Phalloidin has the molecular formula C35H48N8O11S, molecular weight 788.87 and CAS number 17466-45-4. Phalloidin belongs to a class of toxins called phallotoxins, which are isolated from the death cap mushroom (Amanita phalloides). It is a bicyclic peptide that binds to F-actin specifically. Therefore, the distribution of F-actin can be very conveniently studied by using a fluorescent dye-labeled phalloidin. Inside the phalloidin, there is an unusual thioether bridge between cysteine and tryptophan, which can form an inner ring structure. When the pH is raised, the thioether is cleaved and the phalloidin loses its affinity for actin. AbFluor™ 488-Phalloidin selectively bound to F-actin, it is much higher photostability than the fluorescein-phalloidin conjugates. Phalloidin derivatives are convenient probes for labeling, identifying and quantitating F-actin in formaldehyde-fixed and permeabilized tissue sections, which can stain F-actin in cell cultures or cell-free experiments at nanomolar levels.
