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Human IL-4 protein
Human IL-4 protein
- 中文名称:
- Human IL-4 protein
- 英文名称:
- Human IL-4 protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA332527
- 规格:
- 0.01 mg|0.05 mg|0.1 mg|1 mg|2x1 mg
- 保存建议:
- Lyophilized Human IL-4 proteinshould be stored desiccated below -20 degree C. Upon reconstitution, the protein should be Store at 4 degree C between 2-7 days and for future use below -20 degree C. For long term storage it is recommended to add a carrier protein (0.129% HSA or BSA). Please prevent freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- >95 % as determined by SDS-PAGE
- 产品形式:
- Lyophilized from sterile PBS, pH7.4.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Background: Interleukin-4(IL-4), an anti-inflammatory cytokine, plays significant role in pathogenesis of various diseases such as asthma, tumors, and HIV infections. IL-4 is firstly identified as a T cell-derived growth factor for B cells. IL-4 can mediate important pro-inflammatory functions in asthma, including T helper cell type 2 lymphocyte differentiation, induction of IgE production, up-regulation of IgE receptors, expression of vascular cell-adhesion molecule 1, promotion of eosinophil transmigration into the lungs, inhibition of T-lymphocyte apoptosis, and mucus hypersecretion. The role of IL-4 in the pathogenesis of asthma is supported by identification of polymorphisms linked to asthma in the IL-4 gene promoter and proteins involved in IL-4 signaling.