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Recombinant Mouse Bax
Recombinant Mouse Bax
- 中文名称:
- Recombinant Mouse Bax
- 英文名称:
- Recombinant Mouse Bax
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38483
- 规格:
- 0.002 mg|0.01 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Mouse Bax although stable at 12 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- 产品形式:
- The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl.
Sterile Filtered colorless solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: Bax Mouse Recombinant amino acid 38-171 produced in E Coli is a single, non-glycosylated polypeptide chain. The Mouse Bax is purified by proprietary chromatographic techniques.
Introduction: Bcl-2associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.