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Recombinant Human Synaptosomal-associated protein 25kDa
Recombinant Human Synaptosomal-associated protein 25kDa
- 中文名称:
- Recombinant Human Synaptosomal-associated protein 25kDa
- 英文名称:
- Recombinant Human Synaptosomal-associated protein 25kDa
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38520
- 规格:
- 0.01 mg|0.05 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 纯度:
- Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- 产品形式:
- The protein solution contains 20mM Tris-HCl pH7.5, 1mM EDTA, 50mM NaCl and 2mM DTT.
Sterile Filtered colorless solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: SNAP25 Human Recombinant fused to N-terminal His-Tag produced in E Coli is a single, non-glycosylated polypeptide chain containing 226 amino acids and having a molecular mass of 25.4 kDa.
Introduction: Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, SNAP25 product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. The synaptosomal-associated protein (SNAP-25) is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters.