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Recombinant Human Interferon Regulatory Factor-2
Recombinant Human Interferon Regulatory Factor-2
- 中文名称:
- Recombinant Human Interferon Regulatory Factor-2
- 英文名称:
- Recombinant Human Interferon Regulatory Factor-2
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38554
- 规格:
- 0.005 mg|0.02 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 纯度:
- Greater than 95.0% as determined by SDS-PAGE.
- 产品形式:
- 1 mg/ml in 20mM Tris pH-8, 1mM DTT and 10% Glycerol.
Sterile Filtered colorless solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: Interferon Regulatory Factor-2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 133 amino acids (1-113) with a His Tag of 20 aa, and having a molecular mass of 15 kDa.The IRF2 is purified by proprietary chromatographic techniques.
Introduction: Interferon regulatory factor 2 is a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. IRF2 binds to the upstream regulatory region of type-1 IFN and IFN-inducible MHC class-1 genes (the interferon consensus sequence (ics) and represses those genes.