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Recombinant Human Cystatin C
Recombinant Human Cystatin C
- 中文名称：
- Recombinant Human Cystatin C
- 英文名称：
- Recombinant Human Cystatin C
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38628
- 规格：
- 0.005 mg|0.025 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store lyophilized protein at 20 degree C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at 80 degree C for long term storage. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
- 货期：
- 6-8周
- 纯度：
- Greater than 95% as determined by SDS PAGE.
- 产品形式：
- Lyophilized from 0.5mg/mL in 20mM Tris buffer and 50 mM NaCl pH-7.5
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Cystatin-C Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 129 amino acids and having a molecular mass of 14.5 kDa. The protein contains an extra His tag at N-terminus. The Cystatin-C amino acid sequence is identical to UniProtKB/Swiss-Prot entry Q6FGW9 amino acids 28146.The Cystatin-C is purified by proprietary chromatographic techniques.
Introduction: Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.
