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Recombinant Human Myeloid Cell Nuclear Differentiation Antigen
Recombinant Human Myeloid Cell Nuclear Differentiation Antigen
- 中文名称:
- Recombinant Human Myeloid Cell Nuclear Differentiation Antigen
- 英文名称:
- Recombinant Human Myeloid Cell Nuclear Differentiation Antigen
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38673
- 规格:
- 0.002 mg|0.01 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- MNDA although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- Greater than 90.0% as determined by SDS-PAGE.
- 产品形式:
- The MNDA solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.
Sterile Filtered colorless solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: MNDA Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 427 amino acids (1-407 a.a.) and having a molecular mass of 47.9 kDa. The MNDA is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: MNDA plays a role as a transcriptional activator/repressor in the myeloid lineage and in the granulocyte/monocyte cell-specific response to interferon. MNDA Stimulates the DNA binding of the transcriptional repressor protein YY1. MNDA is identified only in nuclei of cells of the granulocyte-monocyte lineage. A 200-a.a region of human MNDA is remarkably related to a region in the proteins encoded by a family of interferon-inducible mouse genes, MNDA participates in blood cell-specific responses to interferons.