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Recombinant Human Frataxin
Recombinant Human Frataxin
- 中文名称:
- Recombinant Human Frataxin
- 英文名称:
- Recombinant Human Frataxin
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38697
- 规格:
- 0.005 mg|0.025 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 纯度:
- Greater than 95.0% as determined by SDS-PAGE.
- 产品形式:
- The Frataxin solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.
Sterile Filtered colorless solution.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: Frataxin Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids (42-210 a.a.) and having a molecular mass of 21.1 kDa. The Frataxin is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: Frataxin is a mitochondrial iron binding protein that is part of the FRATAXIN family. Frataxin functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Frataxin plays a role in iron homeostasis. Frataxin is an anti-apoptotic protein which prevents mitochondrial damage and reactive oxygen species (ROS) production.