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Recombinant Human Estrogen Sulfotransferase
Recombinant Human Estrogen Sulfotransferase
- 中文名称：
- Recombinant Human Estrogen Sulfotransferase
- 英文名称：
- Recombinant Human Estrogen Sulfotransferase
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38701
- 规格：
- 0.005 mg|0.025 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 95.0% as determined by SDS-PAGE.
- 产品形式：
- The SULT1E1 protein solution contains 20mM Tris-HCl, pH-8 and 20% Glycerol.
Sterile filtered colorless solution.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Recombinant Human SULT1E1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (1-294 a.a.) and having a molecular mass of 36.1 kDa. SULT1E1 is fused to 6 amino acid His Tag at C-terminus and purified by conventional chromatography techniques.
Introduction: SULT1E1 catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULTIE1 control the level of the estrogen receptor by sulfurylating free estradiol. maximally sulfates beta-estradiol and estrone at concentrations of 20nm. SULTIE1 in addition sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at considerably higher concentrations; though, cortisol, testosterone and dopamine are not sulfated. Decreased SULT1E1 expression is linked with estrogen-dependent endometrial carcinomas. Altered cellular proliferation was detected in cells stably expressing SULT1E1.
