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Recombinant Human Aldo-Keto Reductase Family 1 Member A1
Recombinant Human Aldo-Keto Reductase Family 1 Member A1
- 中文名称:
- Recombinant Human Aldo-Keto Reductase Family 1 Member A1
- 英文名称:
- Recombinant Human Aldo-Keto Reductase Family 1 Member A1
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA38705
- 规格:
- 0.005 mg|0.02 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- AKR1A1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.
- 货期:
- 6-8周
- 纯度:
- Greater than 90% as determined by SDS-PAGE.
- 产品形式:
- 1mg/ml solution containing 20mM Tris pH-8, 50mM NaCl and 10% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: AKR1A1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 325 amino acids (1-325 a.a.) and having a molecular mass of 36.5 kDa.
AKR1A1 is purified by proprietary chromatographic techniques.
Introduction: AKR1A1 is part of the aldo/keto reductase superfamily, it catalyzes the NADPH-dependent reduction from a range of aromatic and aliphatic aldehydes to their related alcohols. AKR1A1 corresponds (65% identity) to aldose reductase, an enzyme that takes part in the pathogenesis of some diabetic and galactosemic complications. AKR1A1 is involved in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin and daunorubicin.