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Recombinant Human Angiopoietin-like Protein 4, HEK
Recombinant Human Angiopoietin-like Protein 4, HEK
- 中文名称：
- Recombinant Human Angiopoietin-like Protein 4, HEK
- 英文名称：
- Recombinant Human Angiopoietin-like Protein 4, HEK
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38749
- 规格：
- 0.002 mg|0.01 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store lyophilized Angiopoietin-like Protein 4 Human recombinant at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
- 货期：
- 6-8周
- 纯度：
- Greater than 90% as determined by SDS-PAGE.
- 产品形式：
- Filtered and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl pH-7.5.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: The ANGPTL4 Human Recombinant is manufactured with C-terminal fusion of 11 amino acid DYKDDDDK tag. The ANGPTL4 DYKDDDDK-Tagged Fusion Protein is a 44.2kDa protein containing 392 amino acid residues of the Angiopoietin-like Protein 4 and 11 additional amino acid residues - DYKDDDDK tag (underlined).
Introduction: The fasting-induced adipose factor (FIAF, ANGPTL4, PGAR, HFARP) was identified as an adipocytokine up-regulated by fasting, by peroxisome proliferator-activated receptor agonists, and by hypoxia. At the protein level, in human and mouse blood plasma, FIAF was found to be present both as a native protein and in a truncated form. Differentiation of mouse 3T3-L1 adipocytes was associated with the production of truncated FIAF, whereas in human white adipose tissue and SGBS adipocytes, only the native FIAF could be detected. Interestingly, the truncated FIAF was produced by human liver.Experimental data suggest that FIAF is mainly presented in human blood plasma in a truncated form (FIAF-S2), whose level is increased by fenofibrate treatment. Levels of both truncated and native FIAF showed marked inter individual variation but were not associated with body mass index and were not influenced by prolonged semistarvation.
