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Recombinant Human Soluble RANK Ligand, GST Tag
Recombinant Human Soluble RANK Ligand, GST Tag
- 中文名称：
- Recombinant Human Soluble RANK Ligand, GST Tag
- 英文名称：
- Recombinant Human Soluble RANK Ligand, GST Tag
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38752
- 规格：
- 0.002 mg|0.01 mg|0.1 mg|2x0.1 mg|3x0.1 mg
- 保存建议：
- Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 95.0% as determined by SDS-PAGE.
- 产品形式：
- The soluble RANKL protein solution contains 1mM EDTA and PBS pH-7.4.
Sterile Filtered colorelss clear solution.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: RANKL Human Recombinant fused to GST tag produced in E Coli is a single, non-glycosylated polypeptide having a molecular mass of 47 kDa. RANKL is purified by proprietary chromatographic techniques.
Introduction: RANKL binds to tnfrsf11b/opg and to tnfrsf11a/rank. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive t-cell proliferation. May be an important regulator of interactions between t-cells and dendritic cells and may play a role in the regulation of the t-cell-dependent immune response. sRANKL may also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. By injecting soluble RANKL, novel osteopenia model mice were established in only 50 hours. Degree of bone loss can be controlled by changing doses of sRANKL. RANKL can be used in establishing osteopenia model for in vivo screening of drugs for osteoporosis, determination of effect and mechanism, evaluation of bone anabolic drugs.
